Literature associating CCR5 and secondary progressive multiple sclerosis
Chemokine (C-C motif) receptor 5 (gene/pseudogene); Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Synonyms: CCR5, CCR5p, hCCR5, A1A490, B8LFN8 ...