Literature associating CCR2 and tenosynovial giant cell tumor
Monocyte chemoattractant protein 1 receptor; Receptor for the CCL2, CCL7 and CCL13 chemokines. Receptor for the beta-defensin DEFB106A/DEFB106B. Transduces a signal by increasing intracellular calcium ion levels (By similarity). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (Probable).
Synonyms: CCR2, CCR2p, hCCR2, A0A024R2Q0, B4XH69 ...