Disease-gene associations mined from literature

Literature associating SHKBP1 and small intestine neuroendocrine neoplasm

SHKBP1 [ENSP00000291842]

SH3KBP1 binding protein 1; Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation; Belongs to the KCTD3 family.

Synonyms:  SHKBP1,  SHKBP1p,  hSHKBP1,  B3KVX8,  M0QX42 ...

Linkouts:  STRING  Pharos  UniProt