Literature associating TMPRSS3 and autosomal dominant nonsyndromic deafness 2A
Tumor-associated differentially-expressed gene 12 protein; Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro); Belongs to the peptidase S1 family.
Synonyms: TMPRSS3, TMPRSS3p, hTMPRSS3, B7WPR2, P57727 ...