Literature associating ACE and congenital heart disease
Angiotensin I converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety; CD molecules
Synonyms: ACE, D3DU13, J3KRH5, J3KS28, J3KSQ5 ...