DISEASES

Disease-gene associations mined from literature

Literature associating ACE and carotid stenosis

ACE [ENSP00000290866]

Angiotensin I converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety; CD molecules

Synonyms:  ACE,  D3DU13,  J3KRH5,  J3KS28,  J3KSQ5 ...

Linkouts:  STRING  Pharos  UniProt  OMIM