DISEASES

Disease-gene associations mined from literature

Literature associating PGLYRP3 and psoriasis 4

PGLYRP3 [ENSP00000290722]

Peptidoglycan recognition protein intermediate alpha; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Synonyms:  PGLYRP3,  PGLYRP3p,  hPGLYRP3,  Q96LB9,  PGRPIA ...

Linkouts:  STRING  Pharos  UniProt  OMIM