Literature associating RFX5 and severe combined immunodeficiency
Regulatory factor X, 5 (influences HLA class II expression); Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters; Belongs to the RFX family.
Synonyms: RFX5, RFX5p, hRFX5, DKFZP586K091, F2Z2G0 ...