DISEASES

Disease-gene associations mined from literature

Literature associating RFX5 and MHC class II deficiency

RFX5 [ENSP00000290524]

Regulatory factor X, 5 (influences HLA class II expression); Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters; Belongs to the RFX family.

Synonyms:  RFX5,  RFX5p,  hRFX5,  DKFZP586K091,  F2Z2G0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM