DISEASES

Disease-gene associations mined from literature

Literature associating DRC1 and situs inversus

DRC1 [ENSP00000288710]

Coiled-coil domain-containing protein 164; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Required for the assembly and regulation of specific classes of inner dynein arm motors. May also function to restrict dynein-driven microtubule sliding, thus aiding in the generation of ciliary bending.

Synonyms:  DRC1,  DRC1p,  hDRC1,  F8WE02,  Q96MC2 ...

Linkouts:  STRING  Pharos  UniProt