Disease-gene associations mined from literature

Literature associating TIMP4 and thoracic aortic aneurysm

TIMP4 [ENSP00000287814]

Tissue inhibitor of metalloproteinases 4; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9; Tissue inhibitor of metallopeptidases

Synonyms:  TIMP4,  TIMP4p,  hTIMP4,  Q99727,  Q99727p ...

Linkouts:  STRING  Pharos  UniProt  OMIM