DISEASES

Disease-gene associations mined from literature

Literature associating PDE11A and megacystis-microcolon-intestinal hypoperistalsis syndrome

PDE11A [ENSP00000286063]

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively; Phosphodiesterases

Synonyms:  PDE11A,  PDE11Ap,  hPDE11A,  F8WAE1,  F8WDQ4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM