Disease-gene associations mined from literature

Literature associating ADAMTS1 and bulbar polio

ADAMTS1 [ENSP00000284984]

A disintegrin and metalloproteinase with thrombospondin motifs 1; Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture; ADAM metallopeptidases with thrombospondin type 1 motif

Synonyms:  ADAMTS1,  ADAMTS1p,  hADAMTS1,  E5RI60,  E5RJR7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM