Literature associating DISP1 and holoprosencephaly
DISP1 [ENSP00000284476]
Dispatched homolog 1 (Drosophila); Functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal (By similarity). Synergizes with SCUBE2 to cause a increase in SHH secretion; Belongs to the dispatched family.
Synonyms: DISP1, DISP1p, hDISP1, Q96F81, DISPA ...