Literature associating UBP1 and familial hemophagocytic lymphohistiocytosis 3
Upstream binding protein 1 (LBP-1a); Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box; Belongs to the grh/CP2 family. CP2 subfamily.
Synonyms: UBP1, UBP1p, hUBP1, A0A024R2J0, A0A024R2L0 ...