DISEASES

Disease-gene associations mined from literature

Literature associating HHEX and large intestine lipoma

HHEX [ENSP00000282728]

Hematopoietically-expressed homeobox protein HHEX; Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity); NKL subclass homeoboxes and pseudogenes

Synonyms:  HHEX,  F8VU08,  Q03014,  F8VU08p,  hF8VU08 ...

Linkouts:  STRING  Pharos  UniProt  OMIM