Disease-gene associations mined from literature

Literature associating PPM1B and cystinuria

PPM1B [ENSP00000282412]

Protein phosphatase, Mg2+/Mn2+ dependent, 1B; Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser- 172'. Plays an important role in the termination of TNF-alpha- mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB; Belongs to the PP2C family.

Synonyms:  PPM1B,  PPM1Bp,  hPPM1B,  B8ZZF0,  C9JIR6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM