DISEASES

Disease-gene associations mined from literature

Literature associating FBXO4 and adult brain stem glioma

FBXO4 [ENSP00000281623]

F-box only protein 4; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1; F-boxes other

Synonyms:  FBXO4,  FBXO4p,  hFBXO4,  D6RAJ6,  D6RAU6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM