Disease-gene associations mined from literature

Literature associating GUF1 and West syndrome

GUF1 [ENSP00000281543]

Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. ; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.

Synonyms:  GUF1,  GUF1p,  hGUF1,  A0A024R9T3,  D6RBJ0 ...

Linkouts:  STRING  Pharos  UniProt