Literature associating TJP1 and interstitial cystitis
Tight junction protein ZO-1; The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells; Belongs to the MAGUK family.
Synonyms: TJP1, TJP1p, hTJP1, G3V1L9, H0YKB1 ...