Disease-gene associations mined from literature

Literature associating TJP1 and celiac disease

TJP1 [ENSP00000281537]

Tight junction protein ZO-1; The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells; Belongs to the MAGUK family.

Synonyms:  TJP1,  TJP1p,  hTJP1,  G3V1L9,  H0YKB1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM