DISEASES

Disease-gene associations mined from literature

Literature associating CDC42EP2 and familial temporal lobe epilepsy 4

CDC42EP2 [ENSP00000279249]

CDC42 effector protein (Rho GTPase binding) 2; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner; Belongs to the BORG/CEP family.

Synonyms:  CDC42EP2,  O14613,  BORG1,  CEP2,  O14613p ...

Linkouts:  STRING  Pharos  UniProt  OMIM