Disease-gene associations mined from literature

Literature associating FERMT3 and Ghosal hematodiaphyseal syndrome

FERMT3 [ENSP00000279227]

Fermitin family homolog 3; Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity); Belongs to the kindlin family.

Synonyms:  FERMT3,  FERMT3p,  hFERMT3,  F5H1C6,  F5H3I6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM