Disease-gene associations mined from literature

Literature associating SERPING1 and alpha-2-plasmin inhibitor deficiency

SERPING1 [ENSP00000278407]

Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein; Serpin peptidase inhibitors

Synonyms:  SERPING1,  B4E1F0,  B4E1H2,  B5MCB9,  C9JZJ9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM