DISEASES

Disease-gene associations mined from literature

Literature associating GGCT and Pelizaeus-Merzbacher disease

GGCT [ENSP00000275428]

Cytochrome c-releasing factor 21; Catalyzes the formation of 5-oxoproline from gamma- glutamyl dipeptides and may play a significant role in glutathione homeostasis. Induces release of cytochrome c from mitochondria with resultant induction of apoptosis; Belongs to the gamma-glutamylcyclotransferase family.

Synonyms:  GGCT,  B8ZZK2,  GGCT-001,  GGCT-002,  GGCT-004 ...

Linkouts:  STRING  Pharos  UniProt  OMIM