DISEASES

Disease-gene associations mined from literature

Literature associating SRD5A1 and hypospadias

SRD5A1 [ENSP00000274192]

3-oxo-5-alpha-steroid 4-dehydrogenase 1; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

Synonyms:  SRD5A1,  SRD5A1p,  hSRD5A1,  D6RDL6,  D6RG03 ...

Linkouts:  STRING  Pharos  UniProt  OMIM