DISEASES

Disease-gene associations mined from literature

Literature associating POGZ and White-Sutton syndrome

POGZ [ENSP00000271715]

Pogo transposable element with ZNF domain; Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms; DNA transposon derived genes

Synonyms:  POGZ,  A6PW30,  E9PIR8,  E9PJY9,  F5H8H4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM