DISEASES

Disease-gene associations mined from literature

Literature associating PRUNE and imperforate anus

PRUNE [ENSP00000271620]

Drosophila-related expressed sequence 17; Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, migration and differentiation, and acts as a negative regulator of NME1. Plays a role in the regulation of neurogenesis. Involved in the regulation of microtubule polymerization.

Synonyms:  PRUNE,  B7ZB72,  E9PCU1,  PRUNE1,  Q5SZF2 ...

Linkouts:  STRING  Pharos  UniProt