DISEASES

Disease-gene associations mined from literature

Literature associating ZNF750 and ankyloblepharon-ectodermal defects-cleft lip/palate syndrome

ZNF750 [ENSP00000269394]

Zinc finger protein 750; Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.

Synonyms:  ZNF750,  ZNF750p,  hZNF750,  B4DWV0,  I3L0W7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM