DISEASES

Disease-gene associations mined from literature

Literature associating CBX8 and conversion disorder

CBX8 [ENSP00000269385]

Chromobox protein homolog 8; Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility; Chromobox family

Synonyms:  CBX8,  CBX8p,  hCBX8,  C9J6K3,  C9JM54 ...

Linkouts:  STRING  Pharos  UniProt