DISEASES

Disease-gene associations mined from literature

Literature associating ASGR1 and hepatitis

ASGR1 [ENSP00000269299]

C-type lectin domain family 4 member H1; Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface; C-type lectin domain containing

Synonyms:  ASGR1,  ASGR1p,  hASGR1,  I3L129,  I3L1F8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM