DISEASES

Disease-gene associations mined from literature

Literature associating GATA6 and tetralogy of Fallot

GATA6 [ENSP00000269216]

Transcription factor GATA-6; Transcriptional activator. Regulates SEMA3C and PLXNA2. Involved in gene regulation specifically in the gastric epithelium. May regulate genes that protect epithelial cells from bacterial infection. Involved in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression (By similarity). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity); GATA zinc finger domain containing

Synonyms:  GATA6,  GATA6p,  hGATA6,  Q05CA6,  Q92908 ...

Linkouts:  STRING  Pharos  UniProt  OMIM