Literature associating IQGAP1 and pilocytic astrocytoma of cerebellum
IQ motif containing GTPase activating protein 1; Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Synonyms: IQGAP1, IQGAP1p, hIQGAP1, A0A024RC65, H0YKA5 ...