DISEASES

Disease-gene associations mined from literature

Literature associating SFRP5 and ovarian clear cell adenocarcinoma

SFRP5 [ENSP00000266066]

Secreted apoptosis-related protein 3; Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.

Synonyms:  SFRP5,  SFRP5p,  hSFRP5,  Q5T4F7,  FRP1B ...

Linkouts:  STRING  Pharos  UniProt  OMIM