DISEASES

Disease-gene associations mined from literature

Literature associating IDE and familial atrial fibrillation

IDE [ENSP00000265986]

Abeta-degrading protease; Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia; M16 metallopeptidases

Synonyms:  P14735,  Q5T5N3,  R4GN65,  P14735p,  hP14735 ...

Linkouts:  STRING  Pharos  UniProt  OMIM