Literature associating IDE and familial atrial fibrillation
Abeta-degrading protease; Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia; M16 metallopeptidases
Synonyms: P14735, Q5T5N3, R4GN65, P14735p, hP14735 ...