Literature associating ADAM2 and severe congenital neutropenia 4
ADAM2 [ENSP00000265708]
Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing
Synonyms: ADAM2, ADAM2p, hADAM2, ADAM2-001, ADAM2-002 ...