Literature associating PITX1 and Axenfeld-Rieger syndrome type 1
Paired-like homeodomain transcription factor 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb; Belongs to the paired homeobox family. Bicoid subfamily.
Synonyms: PITX1, PITX1p, hPITX1, D6R955, D6R9U1 ...