DISEASES

Disease-gene associations mined from literature

Literature associating MGAT4A and choriocarcinoma

MGAT4A [ENSP00000264968]

UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa; Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells; Mannosyl-glycoprotein N-acetylglucosaminyltransferases

Synonyms:  MGAT4A,  MGAT4Ap,  hMGAT4A,  MGAT4A-001,  MGAT4A-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM