Disease-gene associations mined from literature

Literature associating ARSB and mucopolysaccharidosis type IVB

ARSB [ENSP00000264914]

N-acetylgalactosamine-4-sulfatase; Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation. Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium. In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity); Belongs to the sulfatase family.

Synonyms:  ARSB,  A0A024RAJ9,  E5RHC4,  P15848,  E5RHC4p ...

Linkouts:  STRING  Pharos  UniProt  OMIM