DISEASES

Disease-gene associations mined from literature

Literature associating ICAM1 and Bardet-Biedl syndrome 15

ICAM1 [ENSP00000264832]

Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation; CD molecules

Synonyms:  ICAM1,  ICAM1p,  hICAM1,  B4DNT6,  E7ESS4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM