DISEASES

Disease-gene associations mined from literature

Literature associating DNAJC27 and hereditary desmoid disease

DNAJC27 [ENSP00000264711]

DnaJ (Hsp40) homolog, subfamily C, member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling; DNAJ heat shock proteins

Synonyms:  DNAJC27,  DNAJC27p,  hDNAJC27,  F5GY94,  LOC51277 ...

Linkouts:  STRING  Pharos  UniProt  OMIM