Disease-gene associations mined from literature

Literature associating UFSP2 and Meier-Gorlin syndrome 8

UFSP2 [ENSP00000264689]

UFM1-specific peptidase 2; Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins. Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation; Belongs to the peptidase C78 family.

Synonyms:  UFSP2,  UFSP2p,  hUFSP2,  D6R9J7,  D6RA67 ...

Linkouts:  STRING  Pharos  UniProt  OMIM