Disease-gene associations mined from literature

Literature associating MECOM and myeloid leukemia

MECOM [ENSP00000264674]

Ecotropic virus integration site 1 protein homolog; Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis; Lysine methyltransferases

Synonyms:  MECOM,  C9JU02,  D3DNP4,  E7EPY2,  E7EQ57 ...

Linkouts:  STRING  Pharos  UniProt  OMIM