Literature associating GLRB and glycine encephalopathy
Glycine receptor 58 kDa subunit; Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents.
Synonyms: GLRB, D6R9Y9, D6RD86, GLRB-001, GLRB-002 ...