Disease-gene associations mined from literature

Literature associating IL18RAP and Crohn's disease

IL18RAP [ENSP00000264260]

Interleukin-18 receptor accessory protein; Within the IL18 receptor complex, does not mediate IL18- binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation (PubMed:9792649, PubMed:14528293, PubMed:25500532). May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). ECO:0000269|PubMed:25500532, ECO:0000269|PubMed:9792649,

Synonyms:  IL18RAP,  IL18RAPp,  hIL18RAP,  C9JLE2,  O95256 ...

Linkouts:  STRING  Pharos  UniProt  OMIM