Disease-gene associations mined from literature

Literature associating DGUOK and ophthalmoplegia

DGUOK [ENSP00000264093]

Deoxyguanosine kinase, mitochondrial; Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down- regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents. ECO:0000269|PubMed:17073823, ECO:0000269|PubMed:23043144,

Synonyms:  DGUOK,  A0A0S2Z3N1,  E5KSL5,  E5KSL6,  Q16854 ...

Linkouts:  STRING  Pharos  UniProt  OMIM