DISEASES

Disease-gene associations mined from literature

Literature associating DGUOK and esophageal varix

DGUOK [ENSP00000264093]

Deoxyguanosine kinase, mitochondrial; Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.

Synonyms:  DGUOK,  D6W5I0,  E5KSL5,  E5KSL6,  Q16854 ...

Linkouts:  STRING  Pharos  UniProt  OMIM