Literature associating ACVR1 and fibrodysplasia ossificans progressiva
Serine/threonine-protein kinase receptor R1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity).
Synonyms: ACVR1, ACVR1p, hACVR1, C9J1R3, C9JHJ7 ...