DISEASES

Disease-gene associations mined from literature

Literature associating IL1B and Crohn's disease

IL1B [ENSP00000263341]

Interleukin 1, beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.

Synonyms:  IL1B,  IL1Bp,  hIL1B,  B5BUQ8,  C9JSC2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM