Literature associating HIRA and chromosome 22q11.2 microduplication syndrome
HIRA [ENSP00000263208]
TUP1-like enhancer of split protein 1; Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit; WD repeat domain containing
Synonyms: F5H4M2, HIRA-001, HIRA-002, HIRA-003, HIRA-004 ...